Gene information
Official symbol ADRB3
Official full name adrenoceptor beta 3
Gene type protein-coding gene
Chromosome8p11.23
Gene familyAdrenoceptors
Resources
Entrez Gene 155
HGNC HGNC:288
Ensembl ENSG00000188778
Vega OTTHUMG00000164028
UCSC uc003xkr.3
GO terms: 34 records
GO Description Category LogP Number of genes Detail
GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine GO Biological Processes -5.63167427 4 More
GO:0003013 circulatory system process GO Biological Processes -65.2875605 130 More
GO:0003018 vascular process in circulatory system GO Biological Processes -47.1670528 52 More
GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal GO Biological Processes -12.8867024 12 More
GO:0003073 regulation of systemic arterial blood pressure GO Biological Processes -22.2238525 34 More
GO:0003085 negative regulation of systemic arterial blood pressure GO Biological Processes -9.78130162 11 More
GO:0005975 carbohydrate metabolic process GO Biological Processes -4.30473825 38 More
GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway GO Biological Processes -9.16710904 33 More
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway GO Biological Processes -6.95524830 22 More
GO:0007190 activation of adenylate cyclase activity GO Biological Processes -5.90548425 6 More
GO:0008015 blood circulation GO Biological Processes -65.7270163 119 More
GO:0008217 regulation of blood pressure GO Biological Processes -35.2019435 60 More
GO:0008227 G protein-coupled amine receptor activity GO Molecular Functions -5.63918224 7 More
GO:0031279 regulation of cyclase activity GO Biological Processes -6.38196333 9 More
GO:0031281 positive regulation of cyclase activity GO Biological Processes -5.63918224 7 More
GO:0035150 regulation of tube size GO Biological Processes -44.5138102 41 More
GO:0035296 regulation of tube diameter GO Biological Processes -44.6572858 41 More
GO:0042311 vasodilation GO Biological Processes -18.7593927 16 More
GO:0042803 protein homodimerization activity GO Molecular Functions -14.2815375 77 More
GO:0043235 receptor complex GO Cellular Components -19.4198369 40 More
GO:0043408 regulation of MAPK cascade GO Biological Processes -57.2547066 142 More
GO:0043410 positive regulation of MAPK cascade GO Biological Processes -49.4744054 112 More
GO:0045761 regulation of adenylate cyclase activity GO Biological Processes -6.38434532 8 More
GO:0045762 positive regulation of adenylate cyclase activity GO Biological Processes -5.34310134 6 More
GO:0045776 negative regulation of blood pressure GO Biological Processes -17.1357953 22 More
GO:0051339 regulation of lyase activity GO Biological Processes -7.52607558 10 More
GO:0051349 positive regulation of lyase activity GO Biological Processes -6.76353457 8 More
GO:0071875 adrenergic receptor signaling pathway GO Biological Processes -8.98205881 11 More
GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway GO Biological Processes -9.78130162 11 More
GO:0090066 regulation of anatomical structure size GO Biological Processes -32.7608623 52 More
GO:0097746 blood vessel diameter maintenance GO Biological Processes -44.6572858 41 More
GO:0120161 regulation of cold-induced thermogenesis GO Biological Processes -19.1025541 38 More
GO:0120162 positive regulation of cold-induced thermogenesis GO Biological Processes -19.5569802 32 More
GO:1901338 catecholamine binding GO Molecular Functions -6.56692149 5 More
KEGG pathways: 7 records
KEGG Description Category LogP Number of genes Detail
hsa04020 Calcium signaling pathway KEGG Pathway -10.4415222 36 More
hsa04022 cGMP-PKG signaling pathway KEGG Pathway -9.74555098 16 More
hsa04080 Neuroactive ligand-receptor interaction KEGG Pathway -22.6219922 65 More
hsa04923 Regulation of lipolysis in adipocytes KEGG Pathway -8.97402692 10 More
hsa04924 Renin secretion KEGG Pathway -9.25913478 11 More
hsa04970 Salivary secretion KEGG Pathway -2.31635881 5 More
hsa05207 Chemical carcinogenesis - receptor activation KEGG Pathway -7.05448873 28 More
Drug-Gene interaction
view
Related drugs: 29 records
Drug name Interaction type Source PMID View
amibegron agonist TdgClinicalTrialTTD view
amibegron hydrochloride agonist ChemblInteractions view
amosulalol TTD view
bitolterol TTD view
bopindolol TTD 11752352 view
carteolol hydrochloride antagonist ChemblInteractions view
carvedilol antagonist ChemblInteractions view
carvedilol phosphate antagonist ChemblInteractions view
chembl322862 TTD view
dipivefrin hydrochloride agonist ChemblInteractions view
droxidopa agonist ChemblInteractions 9464897180644171911097019434307 view
epinephrine agonist ChemblInteractions view
epinephrine bitartrate agonist ChemblInteractions view
hydroxyamphetamine hydrobromide agonist ChemblInteractions view
isoproterenol hydrochloride agonist ChemblInteractions view
labetalol hydrochloride antagonist ChemblInteractions view
ly377604 agonist ChemblInteractionsTTD 24900353 view
mephentermine sulfate agonist ChemblInteractions view
mepindolol TTD 6125169 view
mirabegron agonist TdgClinicalTrialChemblInteractionsTTD 23550899 view
nipradilol TTD view
norepinephrine bitartrate agonist ChemblInteractions view
olanzapine PharmGKB 19193342 view
rafabegron agonist ChemblInteractions view
rimiterol TTD view
ritobegron agonist TdgClinicalTrialChemblInteractionsTTD view
solabegron agonist TdgClinicalTrialChemblInteractions 18372395 view
trihexyphenidyl TTD view
vibegron agonist ChemblInteractionsTTD view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
NM_000025.3:c.190T>C genomics myocardial infarction[diagnosis] myocardial infarction Xia K et al. Gene. 2017
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